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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0014fd48986832157de5eb0e42befa549badaf21f5175c6efd93b193441cc638' 
  AND token = '+swn9Qt7r1EP4rP5Lyuj4tIhP5LhaHqiy8VwQJBlfDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}