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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9565e065f51567a4241d8dd48c1613c79e5c1188147c51681ac7317891999345' 
  AND token = 'XmVtSbUrSFsMXm1+LMPIBjZW5ZhVhiD5jpQVtLyfapY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}