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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b41c4b2d7036b7c4e2f80e066e49a761703971309e1ce8b418f4fd7fc9019a' 
  AND token = 'DRHC0JR71aHtoy3xURTtwff/Mk2cmjLdG6Hp/To8mkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}