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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cef76be6ed4915e319001827d9f14be1fcf1bf1efca6cdc61c0461af513702a' 
  AND token = 'cB/nZaIe9tNwofjR/sj/jvW3DHjW8ts74orKnXPg5To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}