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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dce9bc448a1f466360c4b45a3cbcc1fd693d0cfb9d3abab60511765e6214c00' 
  AND token = 'iQZWRIY9VtCEh/SIKhzb5cCDiGHpCEA7VLD4jyeJ9L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}