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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8487a9d0c71a1e2e7ba6dcbed972df9fcf22c6e95080b26517f80c475c080d7b' 
  AND token = 'aZ5b03XIznaEEvFQa9qrB4IDz7vQj6iIARmxEtA2rdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}