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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cdcf80b48d083adaece444bbfcb5933fbe3c1bd888702052e7121c4aa1137d6' 
  AND token = 'xqgpbAsTgaoL04lWScy2+AaqBhuZA+hX17mXYoMWat8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}