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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8224343d6dc97de6cfc2514a7c79511cdd2e0c0e1de261afb885e94d3700ea2f' 
  AND token = 'pdawPFMTRxfgwDJKUnRvskvEZQM5aC3hKCaG/HutXZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}