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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c3f69b4927c108917fdb824535b6649602e196496dc1080597bd8d24e8ff82' 
  AND token = 'NJFE0d6unn9kxPkaAzIycI77zfPqgMF03WxGlbNzo/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}