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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4a25b198cd00411088a0165c5244f4dd19442b72f1c35e753a4dbe44aa399bf' 
  AND token = 'xy40wbLX4/yo/v8K9wmaMck0zxVUsM74HrI6KSReBVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}