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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dfec862f8708a63a2aebdc1ae9232b2531124728e85db83d8d778b84907e032' 
  AND token = 'arVrfHKuRN+yZLQ5HXgl0lNZgGVk1XrL0pzjt24kSTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}