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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f36bd2b98f9c921b009a8ac59c366b2d55698c43809808ce38049f3657a3f823' 
  AND token = 'xXCA45ix/vo0I5y7gmsN/tFdxwfrYwJtKRsg+ps+LsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}