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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1fde1fc72c3dd30d81bb0f8787fc2a4f274c4c5b32011cd082dae21b3d76ac7' 
  AND token = 't1fpwJ7guhtxUPRQQsWho5aEnMo8oBAl3rBd6P8K2uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}