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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ae13ec815d7e3d8449da06a0a68d9c69086fb5c652c1464dd5459fa9f52bfc' 
  AND token = 'wMJHJEGOJGF7BOk+OKj9UMXG8S0lF8GT6Hji7MaID+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}