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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7938681689ec7b7258d8c9e55f3e9fa7181cfc3645d5b7b5b47a2562cafb963' 
  AND token = 'TvzImGTMcT0m/7x3AtLk+CzV37AYvlW1gGYCiM3KGoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}