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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a42a3aa129686e736faa12dc4c97e7f03438ef00594734fcaafb3a666e9c202' 
  AND token = 'hN/SZiQj7S0kVdXvYJKmEJdJq1+HfGMLrM1L14VToCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}