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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3a435e0060853b8dfd87315e23e461ea6ec76a6ea356d401ac0e3a06317d9d' 
  AND token = 'rS5fTITw+SUr0cXJI1HYeNdT4M0CyO7TT/cP6KOhgwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}