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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f1a75b935cf79183c0f310697b21c3a5737da50238b4b41c1d85c57fe44be55' 
  AND token = 'GD67Q6e64ipMfXFidLTGYdjTKsFa7z1Z7J0gFSP1XVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}