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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35e5b026d9bd51c2def3dabc85c796743602a8eb5a7daf2d39a99dc002fcc38' 
  AND token = 'reir3qUUsF+4szvwXPQwLGI1B8bArgUiS3oyVPphCSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}