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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8315fe6dd4f9b613a2756f7dfafe72f84e7a13445e2adc53270ecbd9a0b783c9' 
  AND token = 'rKvWWVjxrQosy4DPZQYcyWrP8ylE5MMT9iPImqMQ2A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}