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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c99a352394e5d56428c791d9294fa64992d06b7c2e65195d192a36ccd5ff5ef' 
  AND token = 'x0t5Zh2vcf3NO83GTx8jbpWUgMfRFpZTTPQTsnGoCwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}