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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76401679266645c0aa784b79818e34f81cc11ac3df8e7d396380091f4bef311' 
  AND token = 'nmtTisN2mu3XuVwRt9pE8msoRcUP/PaVQtuvJuH12UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}