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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca3e8e1bbdce7977b0b7f590a2c3eb221e462b88b67b66ff185e7a1486564b4f' 
  AND token = 'y6PaiXXzEMlAPynA4tK7koCslmLVa1E2oRHblC4ZI3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}