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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e53ab2052a67d95a0a3f3dd6f7d4384074a635b0329c0d5373ba2baef8c14ce' 
  AND token = 'fewUacX8CX2Acid04dIXPZs61qytW7SmlMUUGDI1pU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}