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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a26fef758b93af5800afb461925e157837ed409c3848a8d8d5a0ca5e4cc4649' 
  AND token = '15YnLGahzoF1k0sZuEhaUQh9lVsQulXrnTYYG27QjIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}