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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35ac3b65a2d2562a618971f8b5d0e2d1a26a712c871877610480f937627b7d7b' 
  AND token = 'a90MR1agm4fFNaxZYsckofQLdtYZalpBlTgP3LmgDLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}