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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421066688debc1ba893e18dac4185eb9966da7332dd9c868c6424f4dd81ca1e3' 
  AND token = 'bNw3sbCruI17T4JFEGoGTHuqx0NQNDHEIwwe0htPLCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}