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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed45da3cd83e5b53e7a703221cd337e954d942cbfc3d47bc3a8955e28dccd0ca' 
  AND token = 'pw8Hy1bx4OvG6dAwsRKNgTM5M2JPtZA6OtQTVG+dAeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}