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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14345bc6a44c8948834c0c97769ec70c81b82b2f7afced13376e123a63ca2e2c' 
  AND token = 'uc+a2leP8IoCjF4/c4XB1/1EVPJ23mPI3T8ErI0IM2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}