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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effba8b6c429ec064280c9e98e8ad1739a8629c5178373f5736672cd3ef3e675' 
  AND token = 'gRe+RlKa7UqS8oPN2SXQgbng1td8C+lYA8XjIQ+YCj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}