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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da48304c6d5ad990fb79b5fb9b9e02f88efd77c94cf986864a402a292d1c678' 
  AND token = 'saCThO37AHf+OL3znJmQeQFmuGs9S6rJDbsGOOcqNfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}