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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29b5f284534228e2df1b895d1e77f27364ecf5133eb2632a23fdc513a496a6b' 
  AND token = 'ZAi1+S9BJnxke3Pki9hTD6dCwzT2GgH+UxMZ58BbtjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}