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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfb88e0139ad4551cca2bd64a18e6ee7dfdcc6d2815a5703885714e17c5d51b' 
  AND token = 'qRs0pq4YJUSvWXbsTCRjf98bAMOD0drMqbmAItfUwK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}