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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610c4510e96a691d885a5321c437be2fc722f5a1957561a7fa1b00aa69598633' 
  AND token = 'lp/rR/ceK0p3QtxlFwiBPwDOh5fBWduucuqy+cXsDaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}