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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228f2098de694e840b89243a4cc7f1138619adfa3fa1f2ac8643c4ad340996c2' 
  AND token = 'nAiaYF78GSb/x3eaO4XHbD6dv/08A0xsBmZoO8ZD2II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}