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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8461063d506ee31627bf222f93f267bb6e343f163662e866ace50a0449f5a409' 
  AND token = 'D2kVq5tFpX5T59yS+tnv47r7b1GRWGs7N3nxKoltUtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}