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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41806c6cba902a4d766e4a0e5ddcabdd261b519b8de17a7be5470ce57a024739' 
  AND token = 'RSqVNuS/7NNNLLMoEQfNmTyvmh47Z0sI8y2gjWCeVk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}