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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5907e01eed0f8d81f24c9f1982a3ca3286092859aad284f9385bb8f15fae49bd' 
  AND token = 'Z64dNQSLjp/XEhPKuHf4aqAienH48kxYnPo1SynkNuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}