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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787a1b139d83e5fbf79a18b1c1b2554bdf6be6f73aceefff61146fb4650e57d1' 
  AND token = 'BA2L4cowBCsn9Q9T+4cVRbean4WNbqK4gDKbdm181BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}