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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a3215b3db9644378ad0cfaa74f43b9877937a93aa2c1440b1118d3594856ba' 
  AND token = 'w9ryPPNSnFNenMOfOpkXBFaqykkt7hwXIz79e2osNu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}