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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eff064a59bd131c1af215bf336a5e415f8eccf646ff9245ffe7fc10af28f9cc' 
  AND token = '71TzAlu2lod5e2CVQma/O9w9C78vXWBa7b/A8ogq5B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}