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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aace0126c413d29e364f78ee3cd4abfbe1bb070b94e3f7a4353b5ee38dcce3d' 
  AND token = 'ekEWrNfVR+yBqrsw9eim6jeMPS2H2hgJiUHAqA6Zjc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}