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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad8a22a94210e43a1a5977b4af236a7ca1036282f1daf69b6d18678f95f2062' 
  AND token = 'iMrdLm0nDlFAKhXpEux3AbWGgRttoFyX6iHid0NqsTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}