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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5dd61aba6e24d6a624999be21ae0fd87dbb56ac8beea7e08050e1ec002dd8f' 
  AND token = '4zjx2791GmKCNS7ZLjsie8lFQRvJX4+8o9zewOj68EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}