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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a68a4dd47580a5f783548ad9af9c8c9be5f50234f3c054dda321452e992e07' 
  AND token = 'v4YLUShJnkxL/XySq+LGy4rifR8hZtBafwI7QveMDig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}