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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789eec1087c575d227a9a683ffc7a067da06cd77138c4563dcfb3673be209489' 
  AND token = '2s/UXgATKrHVqieZMickT6oi50WDuAsyfdg47K/aLrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}