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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6480a14b8fd177f25bd2d0f52c91a8c8b482322683bdf63c2cd720a1cbd47fad' 
  AND token = 'iH+b1DAAIX03iJjutxrhnpUytMMz6X3YO8XU/sVMqhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}