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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6b375fa7b79a033f3cb9173bbdc35be0c0509e92a564a4fbf8428cc897e30f' 
  AND token = 'Z5hWVtVEvz1ccByliAeZ6TEJ1CSsIowJYNes8Rk26wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}