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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4730f04cc282ad6f18017db918102270c4f6b3cc8625a0804820246c41cb85dc' 
  AND token = 'S8ACulj4IbolyMUIzU8vS+yZ75Ki9YlLHa9bTPPolLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}