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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448290d5eece101597f7b8f53ad70dc02143ef4c5c2d059334b3bbe381f8be40' 
  AND token = 'onhZcIJNzLKNnSiwbq2ZE6k6KaU4gQGQiRGDCHzz+64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}